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phosphoinositide 3-kinase in health and disease: volume 1
Peter K. Vogt
(Ilustrado por)
·
Christian Rommel
(Ilustrado por)
·
Bart Vanhaesebroeck
(Ilustrado por)
·
Springer
· Tapa Blanda
phosphoinositide 3-kinase in health and disease: volume 1 - Rommel, Christian ; Vanhaesebroeck, Bart ; Vogt, Peter K.
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Reseña del libro "phosphoinositide 3-kinase in health and disease: volume 1"
From humble beginnings over 25 years ago as a lipid kinase activity associated with certain oncoproteins, PI3K (phosphoinositide 3-kinase) has been catapulted to the forefront of drug development in cancer, immunity and thrombosis, with the first clinical trials of PI3K pathway inhibitors now in progress. Here we give a brief overview of some key discoveries in the PI3K area and their impact, and include thoughts on the current state of the field, and where it could go from here
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