The book is a collection of surveys and original research articles concentrating on new perspectives and research directions at the crossroads of algebraic geometry, topology, and singularity theory. The papers, written by leading researchers working on various topics of the above fields, are the outcome of the "Némethi60: Geometry and Topology of Singularities" conference held at the Alfréd Rényi Institute of Mathematics in Budapest, from May 27 to 31, 2019. Both the conference and this resulting volume are in honor of Professor András Némethi, on the occasion of his 60th birthday, whose work plays a decisive and influential role in the interactions between the above fields.The book should serve as a valuable resource for graduate students and researchers to deepen the new perspectives, methods, and connections between geometry and topology regarding singularities.